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HelpTest Code LAB1232641 IgG4, Immunoglobulin Subclasses, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
IgG4, Ig SubclassesSpecimen Type
SerumOrdering Guidance
This test only quantitates the IgG4 protein. If quantitation of all IgG subclass types is desired, order IGGS / IgG Subclasses, Serum.
Specimen Required
Patient Preparation:
Fasting: 12 hours, preferred but not required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Ambient | 14 days | |
| Frozen | 14 days |
Specimen Minimum Volume
Serum: 0.5 mL
Day(s) Performed
Monday through Friday
Specimen Retention Time
14 daysReport Available
1 to 2 daysReference Values
0-<5 months: ≤19.8 mg/dL
5-<9 months: ≤20.8 mg/dL
9-<15 months: ≤22.0 mg/dL
15-<24 months: ≤23.0 mg/dL
2-<4 years: ≤49.1 mg/dL
4-<7 years: ≤81.9 mg/dL
7-<10 years: 1.0-108.7 mg/dL
10-<13 years: 1.0-121.9 mg/dL
13-<16 years: ≤121.7 mg/dL
16-<18 years: ≤111.0 mg/dL
≥18 years: 2.4-121.0 mg/dL
Useful For
Supporting the diagnosis of IgG4-related disease
CPT Code Information
82787
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| IGGS4 | IgG4, Ig Subclasses | 2469-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| IGGS4 | IgG4, Ig Subclasses | 2469-5 |
Method Description
The determination of the soluble antigen concentration by turbidimetric methods involves the reaction with specific antiserum to form insoluble complexes. When light is passed through the suspension formed a portion of the light is transmitted and focused onto a photodiode by an optical lens system. The amount of transmitted light is indirectly proportional to the specific protein concentration in the test sample.
Concentrations are automatically calculated by reference to a calibration curve stored within the instrument.(Package inserts: Optilite IgG4. The Binding Site Group, Ltd; 07/2019)
Disease States
- Humoral immunodeficiency