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HelpTest Code LAB1232590 Buprenorphine and Norbuprenorphine, Chain of Custody, Random, Urine
Useful For
Monitoring of compliance of buprenorphine therapy
Detection and confirmation of the illicit use of buprenorphine
Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was always under the control of personnel involved with testing the specimen; this control implies that the opportunity for specimen tampering would be limited.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| COCH | Chain of Custody Processing | No | Yes |
| ADLTX | Adulterants Survey, CoC, U | Yes | Yes |
Testing Algorithm
Adulterants testing will be performed on all chain-of-custody urine samples as per regulatory requirements.
Reporting Name
Buprenorphine w/metabolite, CoC, USpecimen Type
UrineSpecimen Required
Supplies: Chain of Custody Kit (T282)
Container/Tube: Chain of custody kit containing specimen containers, seals, and required documentation.
Specimen Volume: 5 mL
Collection Instructions: Collect specimen in the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 14 days |
| Ambient | 14 days | |
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Reference Values
Negative
Positive results are reported with a quantitative result.
Cutoff concentrations:
Immunoassay Screen: 5 ng/mL
Liquid chromatography tandem mass spectrometry:
Buprenorphine: 5.0 ng/mL
Norbuprenorphine: 2.5 ng/mL
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80348
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| BUPMX | Buprenorphine w/metabolite, CoC, U | 69033-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 56644 | Buprenorphine Immunoassay Screen | 58359-1 |
| 65215 | Buprenorphine | 3415-7 |
| 48297 | Norbuprenorphine | 49753-7 |
| 56645 | Chain of Custody | 77202-0 |
Forms
1. Chain of Custody Request is included in the Chain-of-Custody Kit (T282).
2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.