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Test Code LAB1232522 Monoclonal Protein Panel

Performing Laboratory

Asante Rogue Regional Medical Center (ARRMC)

 

Performing Department

Special Chemistry

Specimen Required

Specimen Minimum Volume

1.5 ml

Specimen Stability Information

Centrifuge and refrigerate within 2 hours of collection

Refrigerate serum at  2° - 8°C up to 10 days; frozen up to one month.

 

Reject Due To

  • Hemolysis/Hemolyzed
  • Grossly Lipemic, Plasma
  • Quantity not sufficient (QNS)
  • Lacking Two Patient Identifiers:
    • 1-Patient's First & Last name 
    • 2-Patient's Date of Birth

Day(s) Performed

Monday through Friday, AM shift

Method Name

Serum Protein Electrophoresis by Sebia Minicapillary Electrophoresis

Serum Free Light Chains - Turbidimitry

CPT Code Information

  • 83521x2 Immunoglobulin light chains
  • 84165 Protein; electrophoretic fractionation and quantitation, serum 
  • 84155 Protein, total

Billing Code

  • 3009067 x2
  • 3010024
  • 3000602

Profile Information

Monoclonal protein panel includes:

Serum total protein, Serum protein electrophoresis and Serum free light chains

 

Serum protein electrophoresis and/or serum immunofixation alone do not adequately screen for monoclonal gammopathies. Serum free light chains in addition to serum protein electrophoresis increase the likely hood of detecting monoclonal gammopathies or other plasma cell disorders.

 

If a monoclonal protein is found in the Serum Protein Electrophoresis, Serum Immunofixation can be added for characterization.

  • Serum Immunofixation:  Order Test Code: IFES/LAB5171

References:

  1. Katzmann et al. Clin Chem (2009) 55:1517-1522
  2. Dispenzieri et. Al Leukemia (2009) 23, 215-224