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Test Code LAB1232207 Opiate Confirmation, Meconium

Important Note

Mayo's test code: OPATM

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Opiate Confirmation, M

Specimen Type

Meconium


Ordering Guidance


For chain-of-custody testing, order OPTMX / Opiate Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Reject Due To

Grossly bloody Reject; Pink OK
Stool
Diapers		 Reject

Specimen Stability Information

Specimen Type Temperature Time
Meconium Frozen (preferred) 28 days
  Refrigerated  28 days
  Ambient  14 days

Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Day(s) Performed

Monday through Sunday

Specimen Retention Time

2 weeks

Report Available

2 to 3 days

Reference Values

Negative

 

Positives are reported with a quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) result.

 

Cutoff concentrations for LC-MS/MS testing:

Codeine: 20 ng/g

Hydrocodone: 20 ng/g

Hydromorphone: 20 ng/g

Morphine: 20 ng/g

Oxycodone: 20 ng/g

Oxymorphone: 20 ng/g

Useful For

Detecting maternal prenatal opiate/opioid use up to 5 months before birth

CPT Code Information

G0480

80361 (if appropriate for select payers)

80365 (if appropriate for select payers)

Clinical Toxicology CPT Code Client Guidance

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OPATM Opiate Confirmation, M 69026-3

 

Result ID Test Result Name Result LOINC Value
31848 Morphine 69027-1
31850 Oxymorphone 69028-9
31849 Hydromorphone 68541-2
31847 Codeine 68542-0
31852 Oxycodone 68543-8
31851 Hydrocodone 68544-6
31868 Interpretation 8215-6
31869 Chain of Custody 77202-0

Method Description

Meconium is mixed with internal standard and extracted with methanol. The methanolic extract is further processed by solid phase extraction. The extract is analyzed by liquid chromatography tandem mass spectroscopy.(Unpublished Mayo method)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.