Test Code LAB1232205 Amphetamine-Type Stimulants Confirmation, Meconium
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Amphetamines, Confirmation, MSpecimen Type
MeconiumOrdering Guidance
For chain-of-custody testing, order AMPMX / Amphetamine-Type Stimulants Confirmation, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Reject Due To
| Grossly bloody | Reject; Pink OK |
| Stool Diapers |
Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Meconium | Frozen (preferred) | 28 days | |
| Ambient | 28 days | ||
| Refrigerated | 28 days |
Specimen Minimum Volume
0.3 g (approximately 1/4 teaspoon)
Day(s) Performed
Monday through Sunday
Specimen Retention Time
2 weeksReport Available
2 to 3 daysReference Values
Negative
Positives are reported with a quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) result.
Cutoff concentrations for LC-MS/MS testing:
Amphetamine: 20 ng/g
Methamphetamine: 20 ng/g
3,4-Methylenedioxyamphetamine: 20 ng/g
3,4-Methylenedioxyethylamphetamine: 20 ng/g
3,4-Methylenedioxymethamphetamine: 20 ng/g
Useful For
Detecting in utero exposure to amphetamine-type stimulants up to 5 months before birth
CPT Code Information
80324
80359
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AMPHM | Amphetamines, Confirmation, M | 69021-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 31854 | Amphetamine | 43934-9 |
| 31855 | Methamphetamine | 69022-2 |
| 31856 | 3,4-methylenedioxyamphetamine | 69023-0 |
| 31858 | 3,4-methylenedioxyethylamphetamine | 69024-8 |
| 31857 | 3,4-methylenedioxymethamphetamine | 69025-5 |
| 31882 | Interpretation | 69050-3 |
| 31883 | Chain of Custody | 77202-0 |
Method Description
Meconium is mixed with internal standard and extracted with methanol. The methanolic extract is further processed by solid phase extraction. The extract is analyzed by liquid chromatography tandem mass spectroscopy.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.