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HelpTest Code LAB1232163 Thyroglobulin, Tumor Marker Reflex, Serum
Useful For
Reporting of accurate thyroglobulin results, depending on the antithyroglobulin antibodies status of the patient
Accurate measurement of serum thyroglobulin in patients with known or suspected antithyroglobulin autoantibodies or possible heterophile antibodies
Testing Algorithm
This test begins with the analysis of thyroglobulin antibody by immunoassay. If the thyroglobulin antibody result is negative (<1.8 IU/mL), then thyroglobulin testing will be performed by immunoassay.
If the thyroglobulin antibody result is positive (≥1.8 IU/mL), then thyroglobulin testing will be performed by mass spectrometry.
Reporting Name
Thyroglobulin Reflex to MS or IASpecimen Type
Serum RedSpecimen Required
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
1.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | Reject |
Reference Values
Thyroglobulin Antibody: <1.8 IU/mL
THYROGLOBULIN, TUMOR MARKER
Athyrotic: <0.1 ng/mL
Intact thyroid: ≤33 ng/mL
Day(s) Performed
Monday through Friday
Report Available
1 to 6 daysSpecimen Retention Time
6 monthsPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86800
84432 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HTGR | Thyroglobulin Reflex to MS or IA | 56536-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TGABR | Thyroglobulin Antibody, S | 56536-6 |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HTGT | Thyroglobulin, Tumor Marker, IA, S | No | No |
| TGMS | Thyroglobulin, Mass Spec., S | Yes | No |
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.