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Test Code LAB1232051 Alpha-Fetoprotein (AFP), Peritoneal Fluid

Important Note

Mayo's test code: AFPPT

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

AFP, Peritoneal Fluid

Specimen Type

Peritoneal


Specimen Required


Container/Tube: Plain, plastic, screw-top tube

Specimen Volume: 2 mL


Reject Due To

Gross hemolysis Reject
Gross icterus OK

Specimen Stability Information

Specimen Type Temperature Time Special Container
Peritoneal Frozen (preferred) 90 days
  Ambient  7 days
  Refrigerated  7 days

Specimen Minimum Volume

0.5 mL (Samples <0.5 mL may be rejected)

Day(s) Performed

Monday through Saturday

Specimen Retention Time

12 months

Report Available

1 to 3 days

Reference Values

An interpretive report will be provided.

Useful For

An adjunct to cytology to differentiate between malignancy-related ascites and benign causes of ascites formation

CPT Code Information

86316

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AFPPT AFP, Peritoneal Fluid 49761-0

 

Result ID Test Result Name Result LOINC Value
AFPPN AFP, Peritoneal Fluid 49761-0
SITEF Site 39111-0

Supportive Data

An in-house study was performed to select a clinical decision limit to differentiate between malignancy-related and benign causes of ascites with high specificity. The study included 83 cases of benign ascites and 54 cases of malignancy-related ascites. Within the malignancy-related ascites, there were 12 cases of hepatocellular carcinoma (HCC). Using a clinical decision limit cutoff of greater than 6 ng/mL, the specificity was 96% for the benign ascites group. The sensitivity for the HCC was 58%.

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.