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Test Code LAB1232043 Rubeola (Measles) Antibodies, IgG and IgM, Spinal Fluid

Important Note

Mayo code is ROC

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Rubeola (Measles) Ab, IgG,IgM, CSF

Specimen Type

CSF


Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 0.25 mL

Collection Instructions: Submit specimen from collection vial number 2 (preferred), 3, or 4.


Reject Due To

Gross hemolysis OK
Gross lipemia OK

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Specimen Minimum Volume

0.1 mL

Day(s) Performed

Monday through Friday

Specimen Retention Time

14 days

Report Available

1 to 4 days

Reference Values

IgG: <1:5

IgM: <1:10

Reference values apply to all ages.

Useful For

Diagnosing central nervous system rubeola (measles) virus infection and/or subacute sclerosing panencephalitis

CPT Code Information

86765 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ROC Rubeola (Measles) Ab, IgG,IgM, CSF 90254-4

 

Result ID Test Result Name Result LOINC Value
5741 Rubeola (Measles) Ab, IgG 22501-1
5742 Rubeola (Measles) Ab, IgM 22505-2

Method Description

Cerebrospinal fluid (CSF) from a patient is reacted with the antigen substrate. Antibodies, if present, will bind to the antigen forming stable antigen-antibody complexes. If no antibodies are present, the complexes will not be formed, and CSF components will be washed away. Fluorescein labeled antihuman IgG or IgM antibody is added to the reaction site which binds with the complexes formed. This results in a positive reaction of bright apple-green fluorescence when viewed with a properly equipped fluorescence microscope. If no complexes are formed, the fluorescein labeled antibody will be washed away, exhibiting a negative result.(Package insert: Measles Virus Antigen Substrate Slide. AESKU.BION, 02/2025)

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.