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HelpTest Code LAB1232010 Drugs of Abuse Screen, Meconium 4
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Drugs of Abuse Screen, Meconium 4Specimen Type
MeconiumOrdering Guidance
For chain-of-custody testing, order DSM4X / Drugs of Abuse Screen 4, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Reject Due To
| Grossly bloody | Reject, Pink OK |
| Stool Diapers |
Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Meconium | Frozen (preferred) | 21 days |
| Refrigerated | 21 days | |
| Ambient | 72 hours |
Specimen Minimum Volume
0.45 g (approximately 0.5 teaspoon)
Day(s) Performed
Monday through Saturday
Specimen Retention Time
2 weeksReport Available
1 to 2 daysReference Values
Negative
Positives are reported with a quantitative liquid chromatography tandem mass spectrometry result.
Cutoff concentrations by competitive chemiluminescent immunoassay:
Amphetamines: 100 ng/g
Methamphetamine: 100 ng/g
Benzoylecgonine (cocaine metabolite): 100 ng/g
Opiates: 100 ng/g
Tetrahydrocannabinol carboxylic acid (marijuana metabolite): 20 ng/g
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| AMPHM | Amphetamines, Confirmation, M | Yes | No |
| COKEM | Cocaine and Metabolites, Confirm, M | Yes | No |
| OPATM | Opiate Confirmation, M | Yes | No |
| THCM | Carboxy-THC Confirmation, M | Yes | No |
Useful For
Identifying amphetamines (and methamphetamines), opiates, as well as metabolites of cocaine and marijuana in meconium specimens
Testing Algorithm
Testing begins with immunoassay screen. Positive results are confirmed and quantified by liquid chromatography tandem mass spectrometry at an additional charge.
CPT Code Information
80307
80324 (if appropriate)
80359 (if appropriate)
80353 (if appropriate)
80361 (if appropriate)
80365 (if appropriate)
80349 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DASM4 | Drugs of Abuse Screen, Meconium 4 | 49046-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 32078 | Amphetamine | 26895-3 |
| 32080 | Methamphetamine | 27289-8 |
| 32082 | Cocaine | 26956-3 |
| 32084 | Opiate | 29158-3 |
| 32086 | Tetrahydrocannabinol | 26893-8 |
| 32087 | Chain of Custody | 77202-0 |
Method Description
The meconium sample received is screened by competitive chemiluminescent immunoassay by Randox Evidence+ to detect the presence of any of the drugs or drugs that cross react with amphetamine, methamphetamine, cocaine metabolite, opiates, and carboxy-tetrahydrocannabinol. Meconium specimens identified as positive by this screen are analyzed using liquid chromatography tandem mass spectroscopy for the specific drug or drug class indicated.(Unpublished Mayo method)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.