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HelpTest Code LAB1231884 Q Fever IgM and IgG, Titer, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
Q Fever IgM/IgG, Titer, SSpecimen Type
SerumOrdering Guidance
Specimen Required
Only orderable as a reflex. For more information see QFEVR / Q Fever Antibody Screen with Titer Reflex, Serum.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 7 days |
Specimen Minimum Volume
0.25 mL
Day(s) Performed
Monday through Saturday
Specimen Retention Time
14 daysReport Available
Same day/1 to 3 daysReference Values
Only orderable as a reflex. For more information see QFEVR / Q Fever Antibody Screen with Titer Reflex, Serum.
Q fever phase I antibody, IgG
<1:16
Q fever phase II antibody, IgG
<1:16
Q fever phase I antibody, IgM
<1:16
Q fever phase II antibody, IgM
<1:16
Reference values apply to all ages.
Useful For
Diagnosis of Coxiella burnetii, the causative agent of Q fever
Testing Algorithm
For more information see Infective Endocarditis: Diagnostic Testing for Identification of Microbiological Etiology.
CPT Code Information
86638 x 4
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| QFP | Q Fever IgM/IgG, Titer, S | 77175-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80965 | Q Fever Phase I Ab, IgG | 34716-1 |
| 24011 | Q Fever Phase II Ab, IgG | 34717-9 |
| 81115 | Q Fever Phase I Ab, IgM | 9710-5 |
| 24009 | Q Fever Phase II Ab, IgM | 9711-3 |
| 24010 | Interpretation | 69048-7 |
Method Description
An indirect immunofluorescence test is used for the measurement of IgM and IgG antibodies to Coxiella burnetii. Specific antibodies present in the serum of the patient react with rickettsial cells that have been previously fixed on a glass microscope slide. Fluorescein-labeled antihuman IgG or IgM conjugate is used to stain specific antibody bound to the substrate cells. The slides are examined with a fluorescence microscope for characteristic, apple-green fluorescence of the infected cell.(Edligner B. Immunofluorescence serology. A tool for prognosis of Q fever. Diagn Microbiol Infect Dis. 1985;3[4]:343-351; package inserts: Q fever IFA IgG. Focus Diagnostics, Inc; 12/2022; Q fever IFA IgM. Focus Diagnostics, Inc; 12/2022)