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Test Code LAB1231864 Macroprolactin, Serum

Important Note

Mayo code is MCRPL

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Macroprolactin, S

Specimen Type

Serum


Specimen Required


Patient Preparation: For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  90 days
  Ambient  24 hours

Specimen Minimum Volume

0.6 mL

Day(s) Performed

Monday through Sunday

Specimen Retention Time

7 days

Report Available

Same day/1 to 3 days

Reference Values

PROLACTIN, TOTAL

Males

<18 years: not established

≥18 years: 4.0-15.2 ng/mL

Females

<18 years: not established

≥18 years: 4.8-23.3 ng/mL

 

PROLACTIN, UNPRECIPITATED

Males

<18 years: not established

≥18 years: 2.7-13.1 ng/mL

Females

<18 years: not established

≥18 years: 3.4-18.5 ng/mL

 

When the percent of the precipitated (complexed) prolactin fraction of the total prolactin is 60% or less, the result is considered negative for macroprolactin.

Useful For

Determining biologically active levels of prolactin, in asymptomatic patients with elevated prolactin levels

 

Ruling out the presence of macroprolactin

CPT Code Information

84146 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MCRPL Macroprolactin, S 78993-3

 

Result ID Test Result Name Result LOINC Value
PROU Prolactin,Unprecipitated,S 38926-2
T_PRL Prolactin,Total,S 20568-2
RATIO Prolactin, Percent PEG-precipitated 51441-4
CMT42 Interpretive Comment 48767-8

Profile Information

Test ID Reporting Name Available Separately Always Performed
TOPRL Prolactin,Total,S Yes, (order PRL) Yes
PEGPR Prolactin,Unprecipitated,S No Yes

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.