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Test Code LAB1059 Organic Acids Screen, Random, Urine

Important Note

Mayo's test code: OAU

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Reporting Name

Organic Acids Scrn, U

Specimen Type

Urine


Necessary Information


1. Patient's age is required.

2. Biochemical Genetics Patient Information (T602) is recommended, but not required, to be filled out and sent with the specimen to aid in the interpretation of test results.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Pediatric: If insufficient collection volume, submit as much specimen as possible in a single container; the laboratory will determine if volume is sufficient for testing.

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen (preferred) 416 days
  Refrigerated  14 days

Specimen Minimum Volume

4 mL

Day(s) Performed

Monday through Saturday

Specimen Retention Time

2 months

Report Available

3 to 5 days

Reference Values

An interpretive report will be provided.

Useful For

Diagnosis of inborn errors of metabolism

CPT Code Information

83919

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OAU Organic Acids Scrn, U 49287-6

 

Result ID Test Result Name Result LOINC Value
80619 Organic Acids Scrn, U 49287-6

Method Description

A urine volume corresponding to 0.25 mg of creatinine is acidified and then extracted with ethyl acetate. After separation and evaporation of the solvent phase, the dry residue is sialylated and analyzed by capillary gas chromatography mass spectrometry. When indicated, oxidation of 2-keto acids is performed by reaction with hydroxylamine hydrate.(Sweetman L. Organic acid analysis. In: Hommes FA, ed. Techniques in Diagnostic Human Biochemical Genetics. Wiley-Liss; 1991:143-176; Hoffman GF, Feyh P. Organic acid analysis. In: Blau N, Duran M, Blaskovics ME, Gibson KM, eds. Physician's Guide to the Laboratory Diagnosis of Metabolic Diseases. Springer; 2003:27-44; Cowan T, Pasquali M. Laboratory investigations of inborn errors of metabolism. In: Sarafoglou K, Hoffman GF, Roth KS, eds. Pediatric Endocrinology and Inborn Errors of Metabolism. 2nd ed. McGraw-Hill; 2017:1143)

Disease States

  • Alkaptonuria

Forms

1. Biochemical Genetics Patient Information (T602)

2. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.