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HelpTest Code HEPTP Heparin Anti-Xa, Plasma
Useful For
Measuring heparin concentration:
-In patients treated with low-molecular-weight heparin preparations
-In the presence of prolonged baseline activated partial thromboplastin time (APTT) (eg, lupus anticoagulant, "contact factor" deficiency, etc)
-When unfractionated heparin dose needed to achieve desired APTT prolongation is unexpectedly higher (>50%) than expected
This test is not useful for monitoring therapy with the heparinoid "danaparoid."
Reporting Name
Heparin Anti-Xa, PSpecimen Type
Plasma Na CitOrdering Guidance
To test for the presence of inhibitors directed against factor X (FX), order 10INE / Factor X Inhibitor Evaluation, Plasma.
Specimen Required
Specimen Type: Platelet-poor plasma
Collection Container/Tube: Light-blue top (3.2% sodium citrate)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. For complete instructions see Coagulation Guidelines for Specimen Handling and Processing.
2. Centrifuge, aliquot plasma, and centrifuge plasma again.
4. Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.
Additional Information: Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen (preferred) | 14 days | |
| Ambient | 2 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Adult Therapeutic Range
UFH therapeutic range: 0.30-0.70 IU/mL
(6 hours following initiation or dose adjustment)
LMWH therapeutic range: 0.50-1.00 IU/mL for twice daily dosing*
LMWH therapeutic range: 1.00-2.00 IU/mL for once daily dosing*
LMWH prophylactic range: 0.10-0.30 IU/mL
*Sample obtained 4 to 6 hours following subcutaneous injection
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 daySpecimen Retention Time
1 dayPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HEPTP | Heparin Anti-Xa, P | 3274-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| HEPTP | Heparin Anti-Xa, P | 3274-8 |