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HelpTest Code FHBG Hepatitis B Virus Genotyping
Performing Laboratory
ARUP LaboratoriesReporting Name
Hepatitis B Virus GenotypeSpecimen Type
Plasma EDTASpecimen Required
Draw blood in lavender (EDTA) tube(s). Spin down and send 2 mL plasma frozen in a plastic vial.
Required: 1. Viral Load
2. Viral Load Date
Note: Red-top serum and serum gel tube(s) are acceptable.
Note: This test may be unsuccessful if the HBV Viral load is less than log 3.0 or 1,000 IU/mL of plasma.
Reject Due To
| Hemolysis: | NA |
| Thawing: | Warm OK; Cold OK |
| Lipemia: | NA |
| Icterus: | NA |
| Other: | Heparinized specimens |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma EDTA | Frozen (preferred) | 42 days | |
| Refrigerated | 7 days | ||
| Ambient | 72 hours |
Specimen Minimum Volume
0.5 mL
Day(s) Performed
Tuesday, Friday
Report Available
10 to 21 daysReference Values
Interpretive Information: Hepatitis B Virus Genotype
HBV genotype and resistance interpretation is provided by SeqHepB software from Evivar Medical. The following mutations are reported: reverse transcriptase L80I/V, Il69T, V173L, L180M, A181S/T/V, T184A/C/F/I/G/S/M/L, S202C/G/I, M204I/V, N236T, M250I/L/V; surface antigen P120T, D144A, G145R.
Both the HBV RT polymerase and the HBsAg encoding regions are sequenced. Resistance and surface antigen mutations are reported. In addition, the major HBV genotypes are identified. Mutations in viral sub-populations below 20% of total may not be detected.
This test is performed pursuant to a license agreement with Roche Molecular Systems, Inc.
CPT Code Information
87912
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FHBG | Hepatitis B Virus Genotype | 32366-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z3195 | Hepatitis B Genotype | 32366-7 |
| Z3196 | HBV Surface Antigen Mutations | 32366-7 |
| Z3197 | HBV RT Polymerase Mutations | Unable to Verify |