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Test Code CRPCR Carbapenem Resistance Genes, Molecular Detection, PCR, Rectal Swab


Ordering Guidance


This test is performed on rectal and perirectal swab specimens from patients at risk for intestinal colonization with bacteria not susceptible to carbapenem antimicrobials.

 

Other mechanisms of carbapenem resistance, including carbapenemases not targeted by this assay, porin mutations, and hyperexpression of drug efflux pumps, may result in carbapenem resistance. These mechanisms are not detected by this assay.



Specimen Required


Specimen Type: Rectal/perirectal swab

Supplies: Culturette (BBL Culture Swab) (T092)

Container/Tube: Culture transport swab

Specimen Volume: Entire collection


Useful For

Detecting and differentiating the blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP gene sequences associated with carbapenem intermediate or resistant results

 

Aiding in infection control in the detection of gastrointestinal colonization of patients in healthcare settings with bacteria not susceptible to carbapenems using rectal or perirectal swabs

Reporting Name

Carbapenem Resistance Genes, PCR

Specimen Type

Swab

Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time Special Container
Swab Ambient 5 days

Reject Due To

Gross lipemia Reject
Incorrect swab used Reject

Reference Values

Not detected

Supportive Data

The Xpert Carba-R Assay is a US Food and Drug Administration-cleared test. The Xpert Carba-R was further verified for use with a Zeptometrix verification panel and organisms (Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter bacteria) with known carbapenem antimicrobial susceptibility test results. The verification passed, and this test is acceptable for patient testing.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Specimen Retention Time

5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

87798

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRPCR Carbapenem Resistance Genes, PCR 85502-3

 

Result ID Test Result Name Result LOINC Value
IMPCR IMP Resistance Gene 85498-4
VIMCR VIM Resistance Gene 85501-5
NDMCR NDM Resistance Gene 73982-1
KPPCR KPC Resistance Gene 49617-4
OXACR OXA-48-like Resistance Gene 85503-1

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.