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Test Code CRMWS Collapsin Response-Mediator Protein-5-IgG, Western Blot, Serum

Useful For

Evaluation of cases of chorea, vision loss, cranial neuropathy and myelopathy

Reporting Name

CRMP-5-IgG Western Blot, S

Specimen Type

Serum


Ordering Guidance


It is recommended an evaluation be ordered in conjunction with this testing if not previously performed. Multiple neurological phenotype-specific autoimmune/paraneoplastic evaluations are available. For more information as well as phenotype-specific testing options, see Autoimmune Neurology Test Ordering Guide.



Additional Testing Requirements


 



Necessary Information


Provide the following information:

-Relevant clinical information

-Ordering healthcare professional name, phone number, mailing address, and e-mail address



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Negative

Supportive Data

In the Neuroimmunology Laboratory's current clinical service activity, the frequency of collapsin response-mediator protein-5-IgG (CRMP-5-IgG) detection is approximately 2 per 1,000 sera tested, approximating that of the Purkinje cell cytoplasmic autoantibody-type 1 (PCA-1, or anti-Yo). A lung carcinoma was found in 77% of 116 patients, mostly limited small cell type; 6% had thymoma, and 7% had miscellaneous neoplasms.

Day(s) Performed

Monday through Thursday

Report Available

5 to 10 days

Specimen Retention Time

28 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84182

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRMWS CRMP-5-IgG Western Blot, S 47401-5

 

Result ID Test Result Name Result LOINC Value
83107 CRMP-5-IgG Western Blot, S 47401-5