Test Code CLFIB Fibrinogen, Clauss, Plasma
Specimen Required
Only orderable as part of a profile or as a reflex. For more information, see:
AATHR / Thrombophilia Profile, Plasma and Whole Blood
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
ALUPP / Lupus Anticoagulant Profile, Plasma
APROL / Prolonged Clot Time Profile, Plasma
Useful For
Detecting increased or decreased fibrinogen (factor 1) concentration of acquired or congenital origin
Monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis
Reporting Name
Fibrinogen, Clauss, PSpecimen Type
Plasma Na CitSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
Only orderable as part of a profile or as a reflex. For more information, see:
AATHR / Thrombophilia Profile, Plasma and Whole Blood
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
ALUPP / Lupus Anticoagulant Profile, Plasma
APROL / Prolonged Clot Time Profile, Plasma
Males: 200-500 mg/dL
Females: 200-500 mg/dL
In normal full-term newborns and in healthy premature infants (30-36 weeks gestation) fibrinogen is near adult levels (>150) and reaches adult levels by less than 21 days postnatal.
Method Description
The Clauss fibrinogen assay is performed using the HemosIL Fibrinogen-C kit on the Instrumentation Laboratory ACL TOP. Patient plasma, containing fibrinogen, is mixed with reagent containing excess thrombin. The excess thrombin converts the fibrinogen in the patient plasma to fibrin. The amount of time it takes to form a clot is inversely proportional to the amount of fibrinogen present in the patient plasma.(Favaloro EJ, Lippi G. eds. Hemostasis and Thrombosis: Methods and Protocols. 1st ed. Humana Press; 2017)
Day(s) Performed
Monday through Friday
Report Available
1 daySpecimen Retention Time
7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85384
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CLFIB | Fibrinogen, Clauss, P | 48664-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CLFIB | Fibrinogen, Clauss, P | 48664-7 |