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Test Code BNP/LAB106 B-Type Natriuretic Peptide

Performing Laboratory

Asante Rogue Regional Medical Center / Asante Three Rivers Medical Center / Asante Ashland Community Hospital

Specimen Requirements

Lavender-Yellow_K2E EDTA K2  preferred specimen


Specimen may be collected at any time.

Specimen Transport Temperature and Stability

Pearl top tubes with gel separator must be centrifuged immediately after collection. These tubes may be sent directly to the lab after centrifugation without separating the plasma from the cells.


Lavender top tubes without a gel separator in the tube must be centrifuged immediately after collection and separate plasma from cells. Send plasma to the lab for testing. 


Samples should be tested as soon as possible after collection. However, if it is not possible to test the samples immediately, the following is recommended:


Blood and plasma specimens may be stored at room temperature (or chilled 2-8 C.) for testing within 7 hours of collection.

Plasma specimens may be stored chilled (2-8 C.) for testing within 24 hours of collection.

Transport specimens at room temperature or chilled and avoid extreme temperatures.



• For longer storage, transfer at least 500 μL of cell-free sample to a storage tube. Tightly stopper the tube immediately and freeze at -20 °C or colder in a non-defrosting freezer. When thawing, allow samples to equilibrate to room temperature for a minimum of 30 minutes prior to testing.


• Thaw samples only once.


• It is recommended to avoid using severely hemolyzed specimens whenever possible. If a specimen appears to be severely hemolyzed, another specimen should be obtained and tested

Specimen Minimum Volume

0.5 ml

Reasons for Rejection


Quantity not sufficient (QNS)

Lacking Two Patient Identifiers:

         1-Patient's First & Last name 

         2-Patient's Date of Birth

Day(s) Test Set Up

Monday through Sunday

Routine: Monday - Sunday
ASAP - 2 hours after receipt of specimen in the lab
STAT - 1 hour after receipt of specimen in the lab

Additional Information

B-type natriuretic peptide (BNP) is a potent natriuretic, diuretic and vasorelaxant peptide.  It coordinates fluid and electrolyte homeostasis through its activity in the central nervous system and peripheral tissues.  BNP promotes vascular relaxation and lowers blood pressure, particularly in states of hypervolemia.  Its renal effects include increasing glomerular filtration rate and enhancing sodium excretion.  BNP reinforces diuretic effects by suppressing centers for salt appetite.B-Type Natriuretic Peptide (BNP) is a hormone released into the blood in response to increased heart pressure. The BNP test is indicated as an aid in the diagnosis and assessment of severity of congestive heart failure and the risk stratification of patients with acute coronary syndrome.


Chemiluminescence Immunoassay

Performing Department


Test Classification and CPT Coding

83880  -  Description: Natriuretic peptide 

Billing Code