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HelpTest Code APTSC Activated Partial Thromboplastin Time (APTT), Plasma
Necessary Information
Heparin or warfarin therapy should be noted.
Specimen Required
Only orderable as part of a profile or as a reflex. For more information see:
ALUPP / Lupus Anticoagulant Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
AATHR / Thrombophilia Profile, Plasma and Whole Blood
APROL / Prolonged Clot Time Profile, Plasma
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
Useful For
Screening for certain coagulation factor deficiencies and abnormalities (eg, factor VIII, IX, XI, or XII)
Detecting coagulation inhibitors such as lupus anticoagulant, antiphospholipid antibodies, specific factor inhibitors, and nonspecific inhibitors
Evaluating a prolonged activated partial thromboplastin time (APTT) test result to assist in differentiating coagulation factor deficiencies from coagulation inhibitors, especially when the APTT mixing test results are combined with results of other coagulation tests and clinical information
Monitoring heparin (unfractionated) therapy
Reporting Name
Activated Partial Thrombopl Time, PSpecimen Type
Plasma Na CitSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
Only orderable as part of a profile or as a reflex. For more information see:
ALUPP / Lupus Anticoagulant Profile, Plasma
ALBLD / Bleeding Diathesis Profile, Limited, Plasma
AATHR / Thrombophilia Profile, Plasma and Whole Blood
APROL / Prolonged Clot Time Profile, Plasma
ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma
25-37 seconds
The activated partial thromboplastin time (APTT) may be 35% longer in full-term newborns that reach adult reference range by age 3 months and twice the adult upper limit in premature infants reaching adult reference range by age 6 months.
Method Description
The activated partial thromboplastin time (APTT) assay is performed on the Instrumentation Laboratory ACL TOP. Patient plasma is combined and incubated with an APTT reagent containing phospholipid, a negatively charged contact factor activator, and buffer. After a specified incubation time, calcium is added to trigger the coagulation process in the mixture. Subsequently, the time to clot formation is measured optically using a wavelength of 671 nm.(Package insert: HemilsIL SynthASil Instrumentation Laboratory Company; 06/2017)
Day(s) Performed
Monday through Friday
Report Available
Same day/1 daySpecimen Retention Time
7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
85730
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| APTSC | Activated Partial Thrombopl Time, P | 14979-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| APTSC | Activated Partial Thrombopl Time, P | 14979-9 |