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Test Code ALUCR Aluminum/Creatinine Ratio, Random, Urine


Ordering Guidance


The recommended test for routine aluminum screening is AL / Aluminum, Serum

 

For monitoring aluminum exposure or metallic prosthetic implant wear, the preferred test is ALU / Aluminum, 24 Hour, Urine.



Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine collection container with no metal cap or glued insert

Submission Container/Tube: Plastic urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Metals Analysis Specimen Collection and Transport for complete instructions.


Useful For

Monitoring aluminum exposure when a 24-hour urine cannot be collected

 

Monitoring metallic prosthetic implant wear when a 24-hour urine cannot be collected

 

This test is not an acceptable substitute for serum aluminum measurements and is not recommended for routine aluminum screening.

Profile Information

Test ID Reporting Name Available Separately Always Performed
ALCU Aluminum/Creat Ratio, U No Yes
CRETR Creatinine, Random, U No Yes

Reporting Name

Aluminum/Creat Ratio, Random, U

Specimen Type

Urine

Specimen Minimum Volume

0.7 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

ALUMINUM

0-17 years: Not established

≥18 years: <14 mcg/g creatinine

 

CREATININE, RANDOM

0-17 years: Not established

≥18 years: 16-326 mg/dL

Method Description

Aluminum

The metal of interest is analyzed by triple-quadrupole inductively coupled plasma mass spectrometry.(Unpublished Mayo method)

 

Creatinine

The enzymatic method is based on the determination of sarcosine from creatinine with the aid of creatininase, creatinase, and sarcosine oxidase. The liberated hydrogen peroxide is measured via a modified Trinder reaction using a colorimetric indicator. Optimization of the buffer system and the colorimetric indicator enables the creatinine concentration to be quantified both precisely and specifically.(Package insert: Creatinine plus ver 2. Roche Diagnostics; V15.0, 03/2019)

Day(s) Performed

Monday

Report Available

2 to 8 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82570

82108

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ALUCR Aluminum/Creat Ratio, Random, U 13470-0

 

Result ID Test Result Name Result LOINC Value
CRETR Creatinine, Random, U 2161-8
610839 Aluminum/Creat Ratio, U 13470-0