Home
HelpTest Code ADALP Adalimumab Quantitative with Antibody, Serum
Ordering Guidance
If there is a known justification for performing both quantitation and antibody levels, this is the correct test to order. If there is not a known reason to perform the antibody levels component, consider ADALX / Adalimumab Quantitative with Reflex to Antibody, Serum. ADALX testing begins with adalimumab quantitation and only performs testing for antibodies when the quantitation results are 8.0 mcg/mL or less.
Specimen Required
Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.0 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial
Useful For
Therapeutic drug monitoring of adalimumab concentration and antibody levels
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| QNADL | Adalimumab QN, S | Yes, (ADALX) | Yes |
| ABADL | Adalimumab Ab, S | No | Yes |
| INTAD | Adalimumab Interpretation | No | Yes |
Testing Algorithm
For more information see Ulcerative Colitis and Crohn Disease Therapeutic Drug Monitoring Algorithm.
Reporting Name
Adalimumab QN with Antibodies, SSpecimen Type
SerumSpecimen Minimum Volume
0.7 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
| Heat-treated specimens | Reject |
Reference Values
ADALIMUMAB QUANTITATIVE:
Limit of quantitation is 0.8 mcg/mL. Optimal therapeutic ranges are disease specific.
ADALIMUMAB ANTIBODY:
<14.0 AU/mL
Day(s) Performed
Monday, Wednesday, Friday
Report Available
3 to 6 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
80145
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ADALP | Adalimumab QN with Antibodies, S | 99781-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| QNADL | Adalimumab QN, S | 86894-3 |
| ABADL | Adalimumab Ab, S | 90779-0 |
| INTAD | Adalimumab Interpretation | 77202-0 |
Forms
If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.