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Test Code A2PI Alpha-2 Plasmin Inhibitor, Plasma


Specimen Required


Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Platelet-poor plasma

Collection Instructions:

1. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.

2. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.

3. Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.

4. Immediately freeze plasma (no longer than 4 hours after collection) at -20° C or, ideally, -40° C or below.

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. Each coagulation assay requested should have its own vial.


Useful For

Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare)

 

Providing a complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when measured in conjunction with fibrinogen, fibrin D-dimer, fibrin degradation products, soluble fibrin monomer complex, and plasminogen

 

Evaluating liver disease

 

Evaluating the effects of fibrinolytic or antifibrinolytic therapy

Reporting Name

Alpha-2 Plasmin Inhibitor, P

Specimen Type

Plasma Na Cit

Specimen Minimum Volume

Platelet-poor plasma: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Adults: 80-140%

Normal, full-term, and premature infants may have mildly decreased levels (≥50%) that reach adult levels within 90 days postnatal.*

*See Pediatric Hemostasis References section in Coagulation Guidelines for Specimen Handling and Processing.

Day(s) Performed

Monday through Friday

Report Available

3 to 7 days

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

85410

LOINC Code Information

Test ID Test Order Name Order LOINC Value
A2PI Alpha-2 Plasmin Inhibitor, P 27810-1

 

Result ID Test Result Name Result LOINC Value
A2PI Alpha-2 Plasmin Inhibitor, P 27810-1

Forms

If not ordering electronically, complete, print, and send a Coagulation Test Request (T753) with the specimen.