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HelpTest Code A1ALC Alpha-1-Antitrypsin Proteotype S/Z, LC-MS/MS, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Reporting Name
A1AT Proteotype S/Z, LC-MS/MS, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.25 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Specimen Minimum Volume
0.5 mL
Special Instructions
Day(s) Performed
Monday, Thursday
Specimen Retention Time
14 daysReport Available
7 to 14 daysReference Values
ALPHA-1-ANTITRYPSIN:
100-190 mg/dL
ALPHA-1-ANTITRYPSIN PROTEOTYPE:
Negative for S and Z phenotype (Non S Non Z)
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| A1APR | Alpha-1-Antitrypsin Phenotype, S | Yes, (order A1APP) | No |
Useful For
Identification of homozygous and heterozygous S and Z proteotypes of alpha-1-antitrypsin deficiency
Testing Algorithm
If the mass spectrometry proteotype and quantitative serum level are discordant, then phenotyping will be added and performed at an additional charge.
For more information see Alpha-1-Antitrypsin-A Comprehensive Testing Algorithm
CPT Code Information
82103
82542
82104 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| A1ALC | A1AT Proteotype S/Z, LC-MS/MS, S | 102082-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AATP | Alpha-1-Antitrypsin, S | 6771-0 |
| 34855 | A1AT Proteotype S/Z, LC-MS/MS | 49244-7 |
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| A1ASZ | A1AT Proteotype S/Z, LC-MS/MS | No | Yes |
| AATP | Alpha-1-Antitrypsin, S | Yes, (order AAT) | Yes |
Forms
If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.