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Test Code PARCT Malaria Percent Parasitemia

Useful For

Only orderable as a reflex. For more information see LMALP / Malaria PCR with Parasitemia Reflex.

 

Calculation of percent parasitemia that can be used to predict prognosis and monitor response to treatment for patients with malaria and babesiosis

Method Name

Giemsa Stain

Reporting Name

Malaria Percent Parasitemia

Specimen Type

Varies


Specimen Required


Only orderable as a reflex. For more information see LMALP / Malaria PCR with Parasitemia Reflex.

 

Slides for LMALP are used for the PARCT.

 

May be added on to positive LCMAL / Malaria, Molecular Detection, PCR Only by physician request.


Specimen Minimum Volume

Only orderable as a reflex. For more information see LMALP / Malaria PCT with Parasitemia Reflex

Specimen Stability Information

Specimen Type Temperature Time
Varies Refrigerated (preferred) 7 days
  Ambient  7 days

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Clinical Information

Malaria is a potentially life-threatening disease infecting approximately 500 million people and causing 1.5 to 2.7 million deaths annually. It is widespread in sub-Saharan Africa, Central and South America, Hispaniola, the Indian subcontinent, the Middle East, Oceania, and Southeast Asia. In the United States, individuals at risk include travelers and visitors from endemic areas.

 

Examination of the thin film allows for calculation of percent parasitemia, which can be used to predict prognosis and monitor response to treatment for patients with malaria and babesiosis. The degree of parasitemia may change rapidly due to natural parasite replication and administration of antimalarial therapies. Therefore, the percent parasitemia should be calculated upon initial diagnosis and then monitored over time with treatment.

Reference Values

Only orderable as a reflex. For more information see LMALP / Malaria PCR with Parasitemia Reflex.

 

A percent parasitemia is provided following a positive result for Malaria PCR with Parasitemia Reflex

Interpretation

The percentage parasitemia represents the percentage of infected red blood cells. This is calculated from representative microscopic fields on the thin blood film. Gametocytes are not included in the calculation since they are not infectious to humans and are not killed by most antimalaria drugs.

Cautions

Since the degree of parasitemia may change rapidly due to natural parasite replication and administration of antimalarial therapies, it is most useful to calculate the percentage of infected cells immediately after the blood is drawn and malaria parasites are detected. A percent parasitemia that is calculated more than 8 hours after the blood is drawn, will not accurately reflect the patient’s current state of parasitemia.

 

Calculation of the percent parasitemia may not be possible if the malaria parasites are degraded or have altered morphology due to age of the specimen or suboptimal transportation conditions.

 

In some cases of very low parasite burden, a specimen may be PCR positive for Plasmodium species but no organisms are present on the thin film, and therefore it will not be possible to determine the percentage of infected red blood cells.

Method Description

Only orderable as a reflex. For more information see LMALP / Malaria PCR with Parasitemia Reflex.

 

The percentage of infected cells (percent parasitemia) is calculated by counting the number of infected red blood cells among 3,000 to 100,000 red blood cells on the thin blood film. The result is expressed as a percentage (% parasitemia = number of infected red blood cells/total number of red blood cells counted x 100).(Unpublished Mayo method)

Day(s) and Time(s) Performed

Monday through Friday (8 a.m.-4:30 p.m.)

Analytic Time

1 day/Same day

Specimen Retention Time

Until Reported

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test uses a standard method. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

87207

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PARCT Malaria Percent Parasitemia 53556-7

 

Result ID Test Result Name Result LOINC Value
PARCT Malaria Percent Parasitemia 53556-7