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Test Code HAPT/LAB89 Haptoglobin

Performing Laboratory

Asante Rogue Regional Medical Center

Specimen Requirements

Fasting preferred.

Yellow (Gold) top tube (SST)  

Plain Red top tube

Specimen Transport Temperature and Stability

  • Centrifuge collection tube within 2 hours of draw.
  • If samples are not assayed within 8 hours store at 2°-8°C.
  • Freeze aliquoted sample if testing delayed greater than 72 hours.
  • Analyte deterioration may occur in samples that are repeatedly frozen and thawed.

Day(s) Test Set Up

Test performed Monday through Friday, A.M. shift. 

Specimen Minimum Volume

0.5 uL

Reasons for Rejection

Lipemia

Additional Information

Use:  When intravascular hemolysis causes the release of free hemoglobin, binding to haptoglobin occurs, preventing the urinary loss of hemoglobin.  The haptoglobin hemoglobin-complex is then reabsorbed by the reticuloendothelial cells.  When haptoglobin binding capacity is exceeded, free hemoglobin readily passes into the globular filtrate, resulting in hemoglobinuria.
 

Haptoglobin levels are decreased in:  hemolytic anemia, liver disease, genetic anhaptoglobinemia and congenital defects that influence erythrocyte stability.

 

Haptoglobin levels are increased in:  chronic and acute inflammatory disease, neoplastic disease and myocardial infarction.

Methodology

Nephelometry 

Performing Department

Special Chemistry

Test Classification and CPT Coding

83010  Haptoglobin; quantitative

Billing Code

2011120