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Test Code EHRCP Ehrlichia Antibody Panel, Serum

Performing Laboratory

Mayo Medical Laboratories in Rochester

Reporting Name

Ehrlichia Ab Panel

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

Heat-inactivated specimen

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Specimen Minimum Volume

0.25 mL

Day(s) and Time(s) Performed

Monday through Friday; 9 a.m.

Specimen Retention Time

14 days

Analytic Time

Same day/1 day

Reference Values

<1:64

Useful For

As an adjunct in the diagnosis of ehrlichiosis

 

In seroepidemiological surveys of the prevalence of the infection in certain populations

Testing Algorithm

See Acute Tick-Borne Disease Testing Algorithm in Special Instructions.

Method Name

Immunofluorescence Assay (IFA)

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86666 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EHRCP Ehrlichia Ab Panel In Process

 

Result ID Test Result Name Result LOINC Value
81157 Anaplasma phagocytophilum Ab, IgG,S 23877-4
81478 Ehrlichia Chaffeensis (HME) Ab, IgG 47405-6

Clinical Information

See individual unit codes

Interpretation

Serology for IgG may be negative during the acute phase of infection but a diagnostic titer usually appears by the third week after onset.

 

A positive immunofluorescence assay (titer ≥1:64) suggests current or previous infection. In general, the higher the titer, the more likely the patient has an active infection. Four-fold rises in titer also indicate active infection.

 

Previous episodes of ehrlichiosis may produce a positive serology although antibody levels decline significantly during the year following infection.

Cautions

Performance characteristics have not been established for hemolyzed or lipemic specimens.

Clinical Reference

Fishbein DB, Dawson JE, Robinson LE: Human ehrlichiosis in the United States, 1985 to 1990. Ann Intern Med 1994;120:736-743

Method Description

See individual unit codes

Profile Information

Test ID Reporting Name Available Separately Always Performed
ANAP Anaplasma phagocytophilum Ab, IgG,S Yes Yes
EHRC Ehrlichia Chaffeensis (HME) Ab, IgG Yes Yes