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Test Code CA125B/LAB155 CA125

Performing Laboratory

Asante Rogue Regional Medical Center

Specimen Requirements

Yellow (Gold) top tube (SST)

Specimen Transport Temperature and Stability

Centrifuge collection tube and refrigerate within 2 hours of collection

Specimen can be refrigerated at 2° to 8° C for up to 48 hours.

Freeze if testing is to be delayed

Specimen Minimum Volume

2.0 mL

Reasons for Rejection

Hemolysis

Quantity not sufficient (QNS)

Lack of Two Patient Identifiers:

         1-Patient’s First & Last name 

         2-Patient’s Date of Birth

Day(s) Test Set Up

Monday through Sunday

Additional Information

CA 125 levels equal to or greater than 35 U/mL may be found in approximately 1% of healthy individuals and in patients with non-malignant conditions, such as pericarditis, cirrhosis, severe hepatic necrosis, severe endometriosis, first trimester pregnancy and ovarian cysts or in patients with non-ovarian malignancies,
such as uterine carcinoma, hepatoma, pancreatic adenocarcinoma and lung cancers.
A CA 125 value below 35 U/mL does not indicate the absence of residual ovarian cancer because patients with histopathologic evidence of ovarian carcinoma may have CA 125 levels within the range for healthy individuals.  Clinical decisions should not be based on a CA 125 value below 35 U/mL.
Interfering Substances:  ONCOSCINT - administration of ONCOSCINTCR / OV may result in falsely elevated
values in immunoassay including CEA and CA 125.  This interference may persist for months.

Methodology

Chemiluminescence (CLIA)

Performing Department

Chemistry

Test Classification and CPT Coding

86316
Immunoassay for tumor antigen, other antigen, quantitative (eg, CA
50, 72-4, 549), each

Billing Code

2070084